Anotace:
Schizophyllum commune is a widely distributed macrofungal species assorted with bioactivities. The specific objectives were evaluation of antibacterial and antioxidant properties, synthesis of exopolysaccharides and carbohydrates contents estimation of mycelial extract of S. commune under submerged condition. Methanolic extracts of identified S. commune showed highest FRS (92.59%), chelating effect on ferrous ion (79.36%), reducing power (1.844) activities at 16, 1.5, 16 mg/ml concentrations respectively (p<0.05). S. commune showed potent antibacterial activities (p<0.05) against four bacterial strains except against P. aeruginosa where no activity was observed. The maximum inhibition zone was exhibited against S. aureus (20.2 mm) and minimum inhibition was found against B. subtilis (5.0 mm). This study recorded the highest dry weight (9.33 g/L) and rate of average growth (1.33 g/L/day) of S. commune in glucose (p<0.05) medium but highest EPS (4.10 g/L) production was observed in xylose medium. Out of seven nitrogen sources, maximum mycelial yield (2.7 g/L), rate of average growth (0.38 g/L) and EPS (4.26 g/L) were recorded in yeast extract medium (p<0.05). In glucose (0.597 g/100g) and yeast extract (0.006 g/100g) medias, the maximum amount of total carbohydrate was obtained from the EPSs of S. commune. That’s why it may be an excellent source of human medicines.