Recurrent Stroke as a Presenting Feature of Takayasu Arteritis in an Adolescent

Vasiliki Sgouropoulou, Efthymia Vargiami, Maria Kyriazi, Sofia Kafterani, Stella Stabouli, Georgios Tsigaras, Athanasia Anastasiou, Maria Trachana, Dimitrios Zafeiriou

Recurrent Stroke as a Presenting Feature of Takayasu Arteritis in an Adolescent

Číslo: 1/2024
Periodikum: Prague Medical Report
DOI: 10.14712/23362936.2024.6

Klíčová slova: Takayasu arteritis, Adolescent rheumatology, Brain, Stroke.

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Anotace: Takayasu arteritis is a large vessel vasculitis, characterized by granulomatous inflammation of arterial vessels, that typically affects the aorta, its main branches and pulmonary arteries. Disease diagnosis is a challenge and requires awareness of the condition, as clinical signs can be not specific. We report a case of an adolescent with recurrent stroke diagnosed with Takayasu arteritis. A diagnosis of Takayasu arteritis was established due to angiographic findings in the magnetic resonance angiography in conjunction with systolic blood pressure discrepancy, arterial hypertension and increased acute phase reactants. Takayasu arteritis is a rare cause of ischemic stroke in children. However, stroke may be the first manifestation of the disease. Clinical experience and multidisciplinary approach, including aggressive treatment, is essential for the favourable outcome of the disease and the reduction of the associated morbidity and mortality.