The lapicque equation in neuroelectrical stimulation

Tomas Ward, Annraoi DePaor

The lapicque equation in neuroelectrical stimulation

Číslo: 1/2022
Periodikum: Lékař a technika - Clinician and Technology
DOI: 10.14311/CTJ.2022.1.01

Klíčová slova: Lapicque, Hodgkin-Huxley, electrical stimulation, electrophysiology

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Anotace: The Lapicque equation for electrical stimulation of nerve, proposed in 1907 and further discussed in 1909, is applied to the Hodgkin-Huxley neuron, proposed in 1952 and universally recognised nowadays. We demonstrate how an analytical model of the relationship described by Lapicque can be derived through consideration of this mathematical model of the nerve membrane potential when subject to pulsed current input.