Petr Slama, Terezie Zavadilova, Lucie Kratochvilova, Kristina Kharkevich
Effect of peptidoglycan on expression of cd44 on bovine mammary gland lymphocytes
Číslo: Special issue/2019/2020
Periodikum: Journal of Microbiology, Biotechnology and Food Sciences
DOI: 10.15414/jmbfs.2019.9.special.447-448
Klíčová slova: peptidoglycan, lymphocyte, CD44, Staphylococcus aureus, mammary gland, mastitis
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infection caused by peptidoglycan of Staphylococcus aureus. Lymphocytes were obtained by lavage of the mammary glands at four
intervals (24, 48, 72 and 168 hours) following experimental intramammary injection of peptidoglycan. The percentage of CD44 positive
lymphocytes peaked at 24 and 48 hours following infection with peptidoglycan of Staphylococcus aureus. The results show that during
the experimental infection the expression of CD44 on lymphocytes is induced in early stage of mastitis (till 48 hours from the
stimulation of inflammation). In the resolution of mastitis, CD44 expression is dramatically decreased.