Michala Steinerova, Cenek Horecky, Eliska Horecka, Ales Knoll, Sarka Nedomova, Ales Pavlik
Variability of selected genes in relation to the parameters of bones in laying hens
Číslo: Special issue/2019/2020
Periodikum: Journal of Microbiology, Biotechnology and Food Sciences
DOI: 10.15414/jmbfs.2019.9.special.449-452
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analysis of single nucleotide polymorphisms of selected genes encoding non-collagenous proteins (IBSP, SPP1, FN1, MEPE, DCN,
THBS2) with parameters of bones in a group of ISA Brown laying hens. The surveyed parameters were bone breaking strength, length,
width and bone mass. In this pilot study, nineteen samples for genes encoding non-collagenous proteins were tested. The
polymorphisms were detected using PCR method and sequencing. Seven polymorphisms have been discovered in genes encoding noncollagenous proteins in the genes FN1 (c.7413A>G, c.7440+57G>A, c.7440+105G>A, c.7441-71T>C), DCN (c.158C>T) and SPP1
(c.362+117G>C, c.363-88G>C), of which two of these polymorphisms were synonymous and five were in the intron. Despite the
position of the found polymorphisms, no association with the mechanical parameters of the bones were found.